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SEPN
Volume: 108.25K

Septerna Inc (SEPN) P/E Ratio

P/E Ratio as of Oct 26, 2026: -76.07

Average-70.19
Median-69.61
Minimum-76.07
Maximum-65.57
-76.07
6.64 (9.56%)past month
The P/E ratio for Septerna Inc (SEPN) is -76.07 as of Oct 26, 2026. This represents a increase of 136.54% compared to its 12-month average P/E ratio of -32.16. A higher P/E ratio suggests that investors expect strong future earnings growth, while a lower P/E ratio may indicate a potentially undervalued stock or slowing growth.

Septerna Inc P/E Ratio Formula = Stock Price ÷ Earnings Per Share (EPS)

Septerna Inc’s P/E ratio represents the valuation of the company based on its earnings. It’s calculated by dividing the company’s latest stock price by its diluted earnings per share (EPS) over the past 12 months. The P/E ratio helps investors assess how much they are paying for each dollar of earnings, offering valuable insights when comparing Septerna Inc to industry peers.

Septerna Inc (SEPN) P/E Ratio Insights

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Septerna Inc (SEPN) P/E Ratio Historic Data

DateStock priceP/E ratio
Oct 1, 2026$38.05-69.94
Sep 1, 2026$37.68-69.26
Aug 3, 2026$34.98-42.82
Jul 1, 2026$34.61-42.36
Jun 1, 2026$29.98-36.70
May 1, 2026$23.61-21.22
Apr 1, 2026$24.37-21.90
Mar 2, 2026$28.64-18.96
Feb 2, 2026$25.03-16.57
Jan 2, 2026$27.98-18.53

Septerna Inc (SEPN) End of Year P/E Ratio

DateP/E ratioChange
2026-76.07+312.08%
2025-18.46—

FAQs About Septerna Inc (SEPN) P/E ratio

The latest P/E ratio of Septerna Inc (SEPN) is -76.07, as of Oct 26, 2026. This is calculated based on its current stock price and earnings per share (EPS).

Septerna Inc’s last 12-month average P/E ratio is -32.16, compared to its current P/E ratio of -76.07. This reflects a increase of 136.54%.

Septerna Inc’s current P/E ratio of -76.07 is higher than its last 12-month average P/E of -32.16. A higher P/E can indicate strong future growth expectations, while a lower P/E might suggest undervaluation.

Septerna Inc’s average P/E ratio over the last 3 years is -11.72. Comparing this to the current P/E helps assess recent valuation trends and whether the stock is trading above or below its mid-term historical range.

Septerna Inc’s average P/E ratio over the last 5 years is -7.03. A deviation from this historical average may indicate shifts in growth expectations, profitability, or broader market conditions affecting valuation.

Septerna Inc (SEPN)

Volume: 108.25K

Septerna Inc (SEPN) P/E Ratio Insights

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