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SEPN
Volume: 306.43K

Septerna Inc (SEPN) Stock Forecast & Price Target

Septerna Inc (SEPN) Analyst Ratings

Based on 8 analyst ratings
Strong Buy
Strong Buy 63%
Buy 38%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Septerna is facing increased risks in running a CSU study without further clarity, but their decision to wait on Ph2b initiation may enable capital-efficient exploration of SEP-631 in a smaller signal-finding study. Their enthusiasm for their oral PTH asset and Native GPCR platform is increased due to physician interest in novel PTH treatments, leading to a potential for significant market share for their asset SEP-479. With conservative assumptions and a discounted cash flow valuation, Septerna's price objective is estimated to be $40/shr with a 30% probability of approval for their lead MRGPRX2 receptor agonist candidate and 15% probability of approval for their TSHR NAM and GLP-1R/GIPR/GCGR agonist candidates.

Bears say

Septerna is facing substantial risks in its drug discovery and pipeline development, with a low probability of success for its oral native platform and a weak forecast for future revenue and earnings due to competition in multiple therapeutic areas. Recent competitor failures have limited direct read-through, but the company's current strategy and focus on targeting mast cell-driven diseases may not be sufficient for overall success in the market. Despite a strong financial position, with over $500M in cash and securities, the company's ongoing net losses and lack of significant service revenue suggest that investments should be made cautiously.

Septerna Inc (SEPN) has been analyzed by 8 analysts, with a consensus rating of Strong Buy. 63% of analysts recommend a Strong Buy, 38% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Septerna Inc and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Septerna Inc (SEPN) Forecast

Analysts have given Septerna Inc (SEPN) a Strong Buy based on their latest research and market trends.

According to 8 analysts, Septerna Inc (SEPN) has a Strong Buy consensus rating as of Jul 18, 2026. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $41.88, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $41.88, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Septerna Inc (SEPN)

Volume: 306.43K

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