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DNLI
Volume: 70
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Denali Therapeutics (DNLI) Stock Forecast & Price Target

Denali Therapeutics (DNLI) Analyst Ratings

Based on 11 analyst ratings
Buy
Strong Buy 55%
Buy 45%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Denali Therapeutics Inc. is positioned favorably due to the potential significant upside from their ultra-rare ERT settings, particularly in the Pompe disease area, which indicates strong market opportunities. The company's innovative therapeutic approach, including its focus on receptor-targeting mechanisms similar to successful therapies in muscle-targeting knockdown treatments, highlights its competitive edge in addressing neurodegeneration. Additionally, the affirmed regulatory alignment for the MPS 3A program suggests a clear pathway for development that could further enhance the company’s strategic positioning within the biotechnology sector.

Bears say

Denali Therapeutics Inc faces significant downside risks that may adversely affect its financial outlook, including intense competition from companies such as JCR Pharma and RGNX, potential regulatory delays, and pipeline setbacks that could hinder product development. Furthermore, the company anticipates a cost of goods sold (COGS) for its therapeutic candidates to remain around 20%, which may limit profitability and raise concerns about financial sustainability. Additionally, challenges associated with manufacturing and scaling up production could further exacerbate these financial vulnerabilities, making the company’s outlook appear less favorable.

Denali Therapeutics (DNLI) has been analyzed by 11 analysts, with a consensus rating of Buy. 55% of analysts recommend a Strong Buy, 45% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Denali Therapeutics and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Denali Therapeutics (DNLI) Forecast

Analysts have given Denali Therapeutics (DNLI) a Buy based on their latest research and market trends.

According to 11 analysts, Denali Therapeutics (DNLI) has a Buy consensus rating as of Dec 5, 2025. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $32.64, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $32.64, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Denali Therapeutics (DNLI)

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