Allogene Therapeutics Inc

Allogene Therapeutics, Inc. operates as a clinical stage immuno-oncology company pioneering the development and commercialization of genetically engineered allogeneic T cell therapies for the treatment of cancer. The firm develops a pipeline of off-the-shelf T cell product candidates that are designed to target and kill cancer cells. Its engineered T cells are allogeneic, which are derived from healthy donors for intended use in any patient. The company was founded by Arie S. Belldegrun, David D. Chang, David M. Tanen, and Joshua A. Kazam in November 2017 and is headquartered in South San Francisco, CA.

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Allogene Therapeutics reports strong Q4 performance and financial stability

Allogene Therapeutics showcased promising clinical data for its AlloCAR T therapy and emphasized a strong financial position. While facing challenges in manufacturing optimization, the company is focused on pivotal trials and cost management. Opportunities for growth include product reintroductions and ongoing program updates.

Allogene reports positive Q1 results, eyes partnerships for growth

Allogene Therapeutics showcased positive patient responses and financial prudence in Q1 2023, underlining its commitment to innovation and efficiency.
While facing resource limitations and challenges in product development, the company is exploring partnerships and expansion opportunities for future growth.
Overall, Allogene's strategic focus on patient care, operational excellence, and therapeutic advancements positions it well for continued success in the biopharmaceutical industry.

Allogene Therapeutics reports Q2 losses but showcases promising CAR-T results

Allogene Therapeutics' Q2 2023 performance reflects strategic investments in R&D and operational expenses, supported by a strong balance sheet and promising results in their allogeneic CAR-T program.
While facing challenges in patient access, manufacturing, and collaborations, the company is well-positioned to capitalize on opportunities in global expansion, next-gen technologies, and clinical trial progress.
With a focus on innovation, operational efficiency, and market expansion, Allogene Therapeutics navigates complexities in the CAR-T space to drive growth and advance its therapeutic offerings.

Allogene Therapeutics excels in Q3, poised for CAR T leadership

Allogene Therapeutics showcased strong financials, promising clinical trial results, and strategic leadership changes.
The focus on allogeneic CAR T therapy positions the company for growth and market leadership.
Challenges include competition, regulatory complexities, and ensuring manufacturing scalability.
Opportunities lie in expanding trials, presenting at key conferences, and advancing pipeline innovations.

Allogene Therapeutics reports robust financials and advances innovative therapies

Allogene Therapeutics showcased strong financials, innovative trials, and strategic partnerships, positioning the company for future growth and therapeutic advancements.
While facing challenges from external factors and clinical complexities, Allogene has opportunities to expand its therapeutic reach and enhance treatment efficacy.
Investor interest in Allogene's pipeline and the company's positive response to inquiries reflect a promising outlook for continued development and success.
Allogene's focus on cutting-edge therapies, financial stability, and community engagement underscore its commitment to advancing patient care and addressing unmet medical needs.

Allogene Therapeutics reports strong Q1 performance and eyes autoimmune expansion

Allogene Therapeutics demonstrated solid financial performance in Q1 2024, with strategic investments and a focus on core programs.
Challenges in enrollment processes, dosing strategies, and safety considerations underscore the complexities of therapeutic development.
Opportunities lie in expanding into autoimmune indications, leveraging unique treatment approaches, and impacting the CAR T treatment landscape.

Allogene Therapeutics reports Q2 momentum, faces challenges, eyes growth

Allogene Therapeutics demonstrated positive momentum and strategic planning in Q2 2024, focusing on key programs and collaborations.
While financial challenges exist, the company's strengths in manufacturing capabilities and program advancements provide a solid foundation.
Addressing challenges like differentiation in the autoimmune space and financial losses will be crucial for sustained growth.
Opportunities for growth are present in continued program progress, FDA collaborations, and strategic milestones like IND filings.

Allogene Therapeutics advances in CAR-T therapies amidst financial challenges

Allogene Therapeutics showcased promising advancements in Q3 2024 across multiple therapeutic areas, positioning itself as a key player in the CAR-T therapy space.
While financial challenges persist, the company's strong cash position and strategic focus on transformative therapies provide a solid foundation for future growth.
Addressing concerns raised by analysts regarding data, safety, and trial participation will be crucial for maintaining investor confidence and advancing clinical development.
Overall, Allogene's dedication to pioneering treatments in oncology and autoimmune diseases underscores its potential for long-term success and impact in the healthcare sector.

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SOUTH SAN FRANCISCO, Calif., Dec. 23, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer today announced that the U.S. Food & Drug Administration (FDA) has cleared an Investigational New Drug (IND) application to study ALLO-715, Allogene's investigational BCMA AlloCAR T therapy, in combination with nirogacestat, SpringWorks Therapeutics' investigational gamma secretase inhibitor (GSI), in patients with relapsed or refractory multiple myeloma. This combination is part of the company's multi-pronged strategy to develop a treatment for multiple myeloma and will be deployed in the ongoing UNIVERSAL trial. Enrollment in this cohort is expected to begin in the first quarter of 2021.

Allogene Therapeutics Receives IND Clearance from the U.S. Food and Drug Administration for ALLO-715 in Combination with Nirogacestat in Relapsed/Refractory Multiple Myeloma

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Overland Pharmaceuticals will form a $117 million China JV with Allogene Therapeutics to bring allogenic CAR-T drugs to China. Harbour BioMed has out-licensed its fully human SARS-CoV-2 neutralizing antibody, 47D11, to AbbVie.

Week In Review: Week's China Life Science Investments Total $800 Million

SOUTH SAN FRANCISCO, Calif. and BOSTON and SHANGHAI, China, Dec. 15, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, and Overland Pharmaceuticals (“Overland”), a premier biopharmaceutical company backed by Hillhouse Capital, today announced the formation of Allogene Overland Biopharm (Allogene Overland). The joint venture will focus on the development, manufacturing and commercialization of AlloCAR T therapies for patients in greater China, Taiwan, South Korea and Singapore. Allogene Overland will have an exclusive license to develop, manufacture and commercialize specific Allogene candidates targeting BCMA, CD70, FLT3, and DLL3 in the licensed territories. The joint venture will also seek opportunities to advance the global development of AlloCAR T therapies against these targets.

Allogene Therapeutics and Overland Pharmaceuticals Form Joint Venture in Greater China to Develop and Commercialize AlloCAR T™ Cell Therapies

SOUTH SAN FRANCISCO, Calif., Dec. 07, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced preclinical findings of ALLO-605, the Company's first TurboCAR™ clinical candidate and next-generation AlloCAR T therapy for relapsed or refractory multiple myeloma, will be presented in a poster session today at the 62nd Annual Meeting of the American Society of Hematology.

Allogene Therapeutics Presents Preclinical Findings Supporting ALLO-605, the First Anti-BCMA TurboCAR™ T Cell Therapy, at the 62nd Meeting of the American Society of Hematology

SOUTH SAN FRANCISCO, Calif., Dec. 06, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced preclinical findings of ALLO-316, an AlloCAR T™ therapy targeting CD70, in models of acute myeloid leukemia (AML). Data were presented in a poster session today at the 62nd Annual Meeting of the American Society of Hematology.

Allogene Therapeutics Presents Preclinical Data on ALLO-316 in Acute Myeloid Leukemia at the 62nd Meeting of the American Society of Hematology

SOUTH SAN FRANCISCO, Calif., Dec. 05, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced positive initial results from the Phase 1 UNIVERSAL study of ALLO-715 in relapsed/refractory multiple myeloma (MM). Data were presented at an oral session of the American Society of Hematology (ASH) annual meeting. This study utilizes ALLO-647, Allogene's anti-CD52 monoclonal antibody (mAb), as a part of its differentiated lymphodepletion regimen.

Allogene Therapeutics Reports Positive Initial Results from Phase 1 UNIVERSAL Study of ALLO-715 AlloCAR T™ Cell Therapy in Relapsed/Refractory Multiple Myeloma at the 62nd American Society of Hematology Annual Meeting

Allogene Therapeutics (ALLO) reported earnings 30 days ago. What's next for the stock?

Allogene Therapeutics (ALLO) Up 8.4% Since Last Earnings Report: Can It Continue?

SOUTH SAN FRANCISCO, Calif., Dec. 02, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced that management will review initial results presented at the American Society of Hematology Annual Meeting from the ALLO-715 UNIVERSAL Phase 1 trial in relapsed/refractory multiple myeloma on December 5, 2020 via a live webinar at 11:00 AM Pacific Time/2:00 PM Eastern Time.

Allogene Therapeutics Announces Webinar to Review Initial ALLO-715 Phase 1 Data on December 5, 2020

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Allogeneic cell therapies have a significant cost, convenience and efficiency advantage over autologous. Data from three of the leaders: Allogene, Atara and CRISPR are expected in the next 12-to-24 months to further elucidate safety and efficacy.

Regenerative Medicines: Universal Cell Therapy Gaining Momentum

SOUTH SAN FRANCISCO, Calif., Nov. 12, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced that management plans to participate in four investor conferences through the end of the year.

Allogene Therapeutics Announces November and December 2020 Virtual Investor Conference Participation

Allogene Therapeutics' (ALLO) CEO David Chang on Q3 2020 Results - Earnings Call Transcript

Allogene (ALLO) reports no revenues for the third quarter of 2020.

Allogene (ALLO) Q3 Earnings Top Estimates, Pipeline Progresses

SOUTH SAN FRANCISCO, Calif., Nov. 04, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced that it will present initial data from its Phase 1 UNIVERSAL trial of ALLO-715, an anti-BCMA AlloCAR T therapy, in relapsed/refractory multiple myeloma in an oral presentation at the 62nd Annual Meeting of the American Society of Hematology (ASH), taking place virtually December 5 – 8, 2020. Preclinical findings from investigations of ALLO-316, an AlloCAR T targeting CD70 in acute myeloid leukemia and ALLO-605, a BCMA-directed TurboCAR TTM cell therapy in multiple myeloma, will also be presented in poster sessions.

Allogene Therapeutics Announces Oral Presentation of Initial Results from its Phase 1 Dose Escalation Study of ALLO-715 in Relapsed/Refractory Multiple Myeloma at the 62nd Annual Meeting of the American Society of Hematology

SOUTH SAN FRANCISCO, Calif., Nov. 04, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today provided a corporate update and reported financial results for the quarter ended September 30, 2020.

Allogene Therapeutics Reports Third Quarter 2020 Financial Results

SOUTH SAN FRANCISCO, Calif., Oct. 27, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced that it will report third quarter 2020 financial results on Wednesday, November 4, 2020, prior to the open of the market. The announcement will be followed by a live audio webcast and conference call at 5:30 AM Pacific Time/8:30 AM Eastern Time.

Allogene Therapeutics to Report Third Quarter 2020 Financial Results on November 4, 2020

SOUTH SAN FRANCISCO, Calif., Oct. 01, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced that management plans to participate in the Jefferies Virtual Cell Therapy Summit in October 2020.

Allogene Therapeutics Announces October 2020 Virtual Investor Conference Participation

Allogene Therapeutics (ALLO) Down 9.9% Since Last Earnings Report: Can It Rebound?

SOUTH SAN FRANCISCO, Calif., Sept.  02, 2020  (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced that management plans to participate in the following virtual investor conferences in September 2020.

Allogene Therapeutics Announces September 2020 Virtual Investor Conference Participation

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Allogene (ALLO) reports no revenues for the second quarter of 2020.

Allogene's (ALLO) Q2 Loss Widens Y/Y, Pipeline Progresses

Allogene Therapeutics' (ALLO) CEO David Chang on Q2 2020 Results - Earnings Call Transcript

SOUTH SAN FRANCISCO, Calif., Aug.  05, 2020  (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today provided a corporate update and reported financial results for the quarter ended June 30, 2020. 

Allogene Therapeutics Reports Second Quarter 2020 Financial Results

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SOUTH SAN FRANCISCO, Calif., July  28, 2020  (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced that it will report second quarter 2020 financial results on Wednesday, August 5, 2020, prior to the open of the market. The announcement will be followed by a live audio webcast and conference call at 5:30 AM Pacific Time/8:30 AM Eastern Time.

Allogene Therapeutics to Report Second Quarter 2020 Financial Results on August 5, 2020

SOUTH SAN FRANCISCO, Calif., July  07, 2020  (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced the appointment of Thomas F. Gajewski, M.D., Ph.D., and Stephan Grupp, M.D., Ph.D. to its Scientific Advisory Board (SAB). The SAB comprises experts across oncology, immunology, cell therapy, and drug discovery and development.

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