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SYRE

SYRE Stock Forecast & Price Target

SYRE Analyst Ratings

Based on 13 analyst ratings
Strong Buy
Strong Buy 62%
Buy 38%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Spyre Therapeutics is a clinical-stage biotechnology company with a promising pipeline of extended half-life antibodies targeting various diseases and exploring combination treatments. Their focus on multiple mechanisms of action could provide improved convenience and efficacy for patients, and their recent study on anti-TL1A mAb, SPY072, has shown positive results for potential treatment of inflammatory bowel disease, increasing the company's stock target price. With a new clinical program, SKYLIGHT, in place to test combination therapy for hidradenitis suppurativa, the company is also expanding its reach to other inflammatory conditions such as rheumatoid arthritis and psoriatic arthritis. This diversification could lead to increased revenue and growth potential for SYRE in the long term.

Bears say

Spyre Therapeutics is a clinical-stage biotechnology company focused on developing biopharmaceutical products for patients with inflammatory bowel disease and rheumatic diseases. While their pipeline shows promise, their lead candidate SPY002 has similar efficacy to other treatments in the TL1A class and may not have significant additional efficacy when combined with other assets. However, their SKYWAY data could de-risk their upcoming datasets and therefore, their probability of success for SPY230 in UC and CD has been raised to 65% and SPY072 in RA to 70%. The company's current valuation is based on a 6x multiple to projected sales of their clinical-stage candidates with a discounted rate.

SYRE has been analyzed by 13 analysts, with a consensus rating of Strong Buy. 62% of analysts recommend a Strong Buy, 38% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Spyre Therapeutics Inc and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Spyre Therapeutics Inc (SYRE) Forecast

Analysts have given SYRE a Strong Buy based on their latest research and market trends.

According to 13 analysts, SYRE has a Strong Buy consensus rating as of Aug 25, 2026. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $109.38, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $109.38, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Spyre Therapeutics Inc (SYRE)


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