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KPTI
Volume: 487.25K

Karyopharm Therapeutics (KPTI) Stock Forecast & Price Target

Karyopharm Therapeutics (KPTI) Analyst Ratings

Based on 6 analyst ratings
Buy
Strong Buy 33%
Buy 67%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Karyopharm Therapeutics Inc. has demonstrated promising efficacy for its drug XPOVIO (selinexor) in specific patient subgroups, particularly those with TP53 wild-type/pMMR tumors, resulting in a median progression-free survival (mPFS) of 39.5 months. Additionally, the company’s ongoing clinical trials, such as the XPORT-EC-042 trial, suggest potential for a label expansion that could enhance market positioning and share recovery. The observed trends in overall survival (OS) improvements further indicate that selinexor could provide significant benefits over existing therapies, positioning Karyopharm favorably within the competitive landscape of cancer treatments.

Bears say

Karyopharm Therapeutics Inc. faces a negative outlook primarily due to persistent cash constraints and limited commercial success with its multiple myeloma (MM) treatment, XPOVIO (selinexor). The company has encountered delays in its SENTRY trial, with existing data showing a potential deterioration in treatment response by 20-35%, further compounding concerns about market uptake and the viability of its therapies. Additionally, risks such as negative clinical data, regulatory approval challenges, and the possibility of long-term dilution contribute to a cautious valuation adjustment, decreasing projected revenue for XPOVIO from $130 million to $124 million.

Karyopharm Therapeutics (KPTI) has been analyzed by 6 analysts, with a consensus rating of Buy. 33% of analysts recommend a Strong Buy, 67% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Karyopharm Therapeutics and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Karyopharm Therapeutics (KPTI) Forecast

Analysts have given Karyopharm Therapeutics (KPTI) a Buy based on their latest research and market trends.

According to 6 analysts, Karyopharm Therapeutics (KPTI) has a Buy consensus rating as of Apr 9, 2026. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $14.67, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $14.67, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Karyopharm Therapeutics (KPTI)

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