
Ionis Pharma (IONS) Stock Forecast & Price Target
Ionis Pharma (IONS) Analyst Ratings
Bulls say
Ionis Pharmaceuticals has raised its 2025 financial guidance, projecting total revenue of $875-900 million, an increase from the previous estimate of $825-850 million, reflecting strong performances from its drug Tryngolza and other partnered programs. The company reported a positive revenue surprise for Tryngolza, generating $32 million in 3Q25, exceeding the consensus estimate of $24 million, which supports the optimistic outlook for the firm. Additionally, Ionis's clinical pipeline continues to show promise with positive advancements in trials, further solidifying its position as a leader in antisense technology and contributing to an overall optimistic financial trajectory.
Bears say
Ionis Pharmaceuticals has reported significant financial losses, with no anticipated profitability for several years, raising concerns over its ongoing financial sustainability. The company's cash and equivalents decreased from $2.3 billion at the end of Q2 2025 to $2.24 billion at the end of Q3 2025, indicating cash flow challenges. Additionally, there are multiple risks impacting its outlook, including potential market share erosion for Spinraza, slower-than-expected uptake of new therapies, and delays in securing regulatory approvals for its key pipeline candidates.
This aggregate rating is based on analysts' research of Ionis Pharma and is not a guaranteed prediction by Public.com or investment advice.
Ionis Pharma (IONS) Analyst Forecast & Price Prediction
Start investing in Ionis Pharma (IONS)
Order type
Buy in
Order amount
Est. shares
0 shares