
CytomX Therapeutics (CTMX) Stock Forecast & Price Target
CytomX Therapeutics (CTMX) Analyst Ratings
Bulls say
CytomX Therapeutics has demonstrated strong demand for its CX-2051 trial, which has expanded enrollment to approximately 100 patients, compared to around 73 patients as of August 2025. The company is optimistic about achieving a 15-20% objective response rate (ORR) among expansion cohorts, which would significantly enhance the prospects for regulatory approval. Furthermore, preliminary data suggesting a median progression-free survival (mPFS) of 5.8 months indicates that CX-2051 could outperform standard of care (SOC), potentially leading to substantial upside for the company's stock when the data update is released in the first quarter of 2026.
Bears say
CytomX Therapeutics reported a decline in cash and investments, with a total of $143.6 million in the third quarter of 2025, down from $158.1 million in the second quarter, indicating potential liquidity challenges. The company's reliance on the EpCAM target is concerning due to historical issues with toxicity, including on-target off-tumor effects, which may lead to significant hurdles in product development and market acceptance. Moreover, the anticipated high rate of Grade ≥3 diarrhea, which may require a black box warning if approved, raises additional doubts about the safety profile of its therapeutics, impacting investor confidence.
This aggregate rating is based on analysts' research of CytomX Therapeutics and is not a guaranteed prediction by Public.com or investment advice.
CytomX Therapeutics (CTMX) Analyst Forecast & Price Prediction
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