Applied Therapeutics Inc

Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company which engages in the development of a pipeline of novel products. It is targeting treatments for central nervous system rare diseases and diabetic complications. The company was founded by Shoshana Shendelman on January 20, 2016 and is headquartered in New York, NY.

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NEW YORK, Jan.  28, 2020  (GLOBE NEWSWIRE) -- Applied Therapeutics, Inc. (NASDAQ: APLT) (the “Company”), a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need, today announced it has completed its public offering of 3,152,712 shares of its common stock.  The offering consisted of 3,152,712 shares of common stock, including the exercise in full of the underwriters’ option to purchase 411,223 additional shares of common stock.  The shares were offered at a price to the public of $45.50 per share, resulting in aggregate gross proceeds of approximately $143.4 million, before deducting underwriting discounts and commissions and estimated offering expenses. 

Applied Therapeutics, Inc. Announces Closing of Public Offering and Exercise in Full of the Underwriters’ Option to Purchase Additional Shares of Common Stock

NEW YORK, Jan.  23, 2020  (GLOBE NEWSWIRE) -- Applied Therapeutics, Inc. (NASDAQ: APLT) (the “Company”), a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need, today announced the pricing of its public offering of 2,741,489 shares of its common stock, par value $0.0001 per share, at a price to the public of $45.50 per share. The gross proceeds to the Company from the offering, before deducting the underwriting discounts and commissions and estimated offering expenses payable by the Company, are expected to be approximately $124.7 million. In addition, the Company has granted the underwriters a 30-day option to purchase up to an additional 411,223 shares of common stock at the price to the public, less underwriting discounts and commissions. The offering was upsized from the previously announced offering size of 1,750,000 shares of common stock. 

Applied Therapeutics, Inc. Announces Upsizing and Pricing of Public Offering of 2,741,489 Shares of Common Stock

NEW YORK, Jan.  21, 2020  (GLOBE NEWSWIRE) -- Applied Therapeutics, Inc. (NASDAQ: APLT) (the “Company”), a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need, today announced that it plans to make a public offering of 1,750,000 shares of its common stock, par value $0.0001 per share, in an underwritten registered public offering. The Company expects to grant the underwriters a 30-day option to purchase up to 262,500 additional shares of common stock.

Applied Therapeutics, Inc. Announces Offering of 1,750,000 Shares of Common Stock

As of late, it has definitely been a great time to be an investor Applied Therapeutics.

Applied Therapeutics Shares March Higher, Can It Continue?

Applied Therapeutics (APLT) soars on positive top-line results from the mid-stage study in adult Galactosemia patients on pipeline candidate, AT-007.

Applied Therapeutics Up on Positive Galactosemia Study Data

Applied Therapeutics (APLT) news for Wednesday concerning positive results from a clinical trial have APLT stock rocketing higher.
The post Applied Therapeutics News: APLT Stock Shoots 32% Higher on Positive Clinical Trial Results appeared first on InvestorPlace.

Applied Therapeutics News: APLT Stock Shoots 32% Higher on Positive Clinical Trial Results

Stellar results from a phase 2 study have investors excited about the biotech's prospects.

Here's Why Applied Therapeutics Rocketed Higher Today

Shares of Applied Therapeutics Inc. APLT, -2.06% jumped 27% in premarket trading on Wednesday after the company said it had positive results from a Phase-2 clinical trial testing AT-007 as a treatment for a rare metabolic disorder.

Applied Therapeutics' stock is up on mid-stage results for metabolic drug

AT-007 demonstrated a robust and sustained reduction in galactitol vs placebo; significant plasma galactitol reduction of ~50% (p

Applied Therapeutics Announces Positive Topline Results of Pivotal Phase 2 ACTION-Galactosemia Study of AT-007 in Galactosemia Patients

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NEW YORK, Dec.  16, 2019  (GLOBE NEWSWIRE) -- Applied Therapeutics Inc. (Nasdaq:APLT), announced today that Shoshana Shendelman, Ph.D., Founder, Chief Executive Officer and Chair of the Board, will ring the Nasdaq Closing Bell on Tuesday, December 17, 2019, at 4:00 p.m. ET.

Applied Therapeutics to Ring Nasdaq Closing Bell on December 17th

NEW YORK, Dec.  06, 2019  (GLOBE NEWSWIRE) -- Applied Therapeutics Inc. (Nasdaq:APLT), a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need, today announced the presentation of data at the World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease (WCIRDC) in Los Angeles (December 4-7, 2019) on AT-001, a novel, potent and selective aldose reductase inhibitor (ARI) in Phase 3 clinical development for Diabetic Cardiomyopathy (DbCM).

Applied Therapeutics Announces Presentation of Pre-Clinical Data Highlighting AT-001 for Treatment of Diabetic Cardiomyopathy at the World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease (WCIRDC)

NEW YORK, Dec.  05, 2019  (GLOBE NEWSWIRE) -- Applied Therapeutics Inc. (Nasdaq:APLT), a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need, today announced poster and oral presentations at the 16th Annual Global Cardiovascular Clinical Trialist’s Forum (CVCT) in Washington, D.C. (Embassy of France, December 5-7, 2019) outlining the design and rational for the ARISE-HF study. ARISE-HF is a Phase 3 pivotal study examining effects of AT-001, a novel, potent and selective aldose reductase inhibitor (ARI), on functional capacity (as measured by peak V02) in patients with Diabetic Cardiomyopathy (DbCM) at high risk of progression.

Applied Therapeutics Announces Presentations Outlining the Design and Rationale for the ARISE-HF Pivotal Study of AT-001 for Treatment of Diabetic Cardiomyopathy at the 16th Annual Global Cardiovascular Clinical Trialist’s Forum (CVCT)

NEW YORK, Nov.  12, 2019  (GLOBE NEWSWIRE) -- Applied Therapeutics, Inc. (NASDAQ: APLT) (the “Company”), a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need, today announced it has entered into a definitive securities purchase agreement, dated as of November 7, 2019, for the sale of its common stock, par value $0.0001 per share (the “Shares”), in a private placement (the “Private Placement”) expected to result in gross proceeds to the Company of approximately $20 million, before deducting placement agent commissions and other offering expenses.

Applied Therapeutics, Inc. Announces Pricing of $20 Million Private Placement of Common Stock

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NEW YORK, Sept.  17, 2019  (GLOBE NEWSWIRE) -- Applied Therapeutics Inc. (Nasdaq:APLT), a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need, today announced presentation of data at the 55th Annual Meeting of the European Association for the Study of Diabetes (EASD) in Barcelona (September 16-20, 2019) on AT-001, a novel, potent and selective aldose reductase inhibitor (ARI) in Phase 3 clinical development for Diabetic Cardiomyopathy (DbCM).

Applied Therapeutics to Present Preclinical Data Highlighting AT-001 for the Treatment of Diabetic Cardiomyopathy at the 55th Annual Meeting of the European Association for the Study of Diabetes (EASD)

NEW YORK, Sept.  13, 2019  (GLOBE NEWSWIRE) -- Applied Therapeutics Inc. (Nasdaq:APLT), a clinical-stage biopharmaceutical company developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need, today announced presentation of data at the Heart Failure Society of America (HFSA) 23rd Annual Scientific Meeting in Philadelphia (September 13-16, 2019) on AT-001, a novel, potent and selective aldose reductase inhibitor (ARI) in Phase 3 clinical development for Diabetic Cardiomyopathy (DbCM). The presentation, titled “Preclinical and Clinical Proof of Concept for Metabolic Intervention in Diabetic Cardiomyopathy,” further supports the development rationale and clinical proof of concept for AT-001 in DbCM. 

Applied Therapeutics to Present Data Highlighting AT-001 for the Treatment of Diabetic Cardiomyopathy at the Heart Failure Society of America (HFSA) 23rd Annual Scientific Meeting

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