
Alnylam Pharmaceuticals (ALNY) Stock Forecast & Price Target
Alnylam Pharmaceuticals (ALNY) Analyst Ratings
Bulls say
Alnylam Pharmaceuticals demonstrated strong financial performance in 2025, achieving combined net product revenues of approximately $2,987 million, which reflects an impressive 81% year-over-year growth that surpassed the company's guidance by over $800 million. The company's gross margin remained robust, supported by significant operating leverage, and its Rare franchise showed steady double-digit growth, contributing around $500 million annually. Furthermore, the positive outlook is bolstered by expected growth in research and development and selling, general, and administrative expenses, indicating ongoing commitment to enhancing product development and pipeline expansion.
Bears say
Alnylam Pharmaceuticals is facing a negative outlook due to expected sequential revenue declines and diminishing growth prospects, with management forecasting 1Q26 growth to be considerably lower than 4Q25 attributed to transitory factors. The company's gross margin, projected at approximately 77% for 2025, has seen a modest decline year-over-year due to tiered royalty escalations and anticipated mid-single-digit net price reductions for Amvuttra, significantly impacting international revenues. Furthermore, Alnylam's collaboration revenue is expected to drop significantly in 2026, with guidance indicating a forecast of $400 million to $500 million, a stark decrease from 2025 levels that were inflated by a non-recurring milestone of $300 million.
This aggregate rating is based on analysts' research of Alnylam Pharmaceuticals and is not a guaranteed prediction by Public.com or investment advice.
Alnylam Pharmaceuticals (ALNY) Analyst Forecast & Price Prediction
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