Novartis

Novartis AG is a holding company, which engages in the development, manufacture, and marketing of healthcare products. It operates through the following segments: Innovative Medicines, Sandoz, and Corporate. The Innovative Medicines segment researches, develops, manufactures, distributes and sells patented pharmaceuticals, and is composed of two business units: Novartis Oncology and Novartis Pharmaceuticals. The Sandoz segment develops, manufactures and markets finished dosage form medicines as well as intermediary products, including active pharmaceutical ingredients. The Corporate segment refers to group management and central services. The company was founded on February 29, 1996 and is headquartered in Basel, Switzerland.

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Novartis AG is a holding company, which engages in the business of developing, manufacturing, and marketing healthcare products. It operates through the following segments: Innovative Medicines, Sandoz, and Corporate. The Innovative Medicines segment includes researching, distributing and selling patented pharmaceuticals. The Sandoz segment focuses on marketing finished dosage form medicines and intermediary products including active pharmaceutical ingredients. The Corporate segment is involved in group management and central services. The company was founded on February 29, 1996 and is headquartered in Basel, Switzerland.

Novartis' (NVS) CAR-T cell therapy Kymriah (tisagenlecleucel) gets an FDA approval for a third indication.

Novartis (NVS) Wins FDA Nod for Label Expansion of Kymriah

Basel, May 28, 2022 — Novartis today announced the US Food and Drug Administration (FDA) has granted accelerated approval for Kymriah® (tisagenlecleucel) for the treatment of adult patients with relapsed or refractory (r/r) follicular lymphoma (FL) after two or more lines of systemic therapy. In accordance with the Accelerated Approval Program, continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trial(s). Kymriah is now FDA approved in three indications and remains the only CAR-T cell therapy approved in both adult and pediatric settings1. "We are proud of today's FDA approval of a third indication for Kymriah. We hope this treatment option that has the potential for long-lasting results may help break the unrelenting cycle of treatment for patients with follicular lymphoma,” said Victor Bulto, President, Novartis Innovative Medicines US. “We are on a mission to build on our pioneering work in cell therapy and continue to innovate for patient impact.”

FDA approves Novartis Kymriah® CAR-T cell therapy for adult patients with relapsed or refractory follicular lymphoma

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Novartis (NVS) Cosentyx gets a positive CHMP recommendation for the indication of juvenile idiopathic arthritis.

Novartis (NVS) Cosentyx Gets Positive CHMP Opinion for JIA

Basel, May 20, 2022 — Novartis today announced the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion for Cosentyx® (secukinumab), used alone or in combination with methotrexate, in the juvenile idiopathic arthritis (JIA) categories of enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA) in patients 6 years and older whose disease has responded inadequately to, or who cannot tolerate, conventional therapy8.

Novartis Cosentyx® (secukinumab) receives positive CHMP opinion for expanded use in childhood arthritic conditions

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Basel, May 12, 2022 — Novartis highlights data from across its oncology portfolio at the upcoming 2022 American Society of Clinical Oncology (ASCO) Annual Meeting and the European Hematology Association (EHA) 2022 Hybrid Congress. With nearly 130 abstracts from Novartis-sponsored and investigator-initiated trials accepted, the data showcase research across over 20 compounds in key disease areas, including breast, lung and prostate cancers, leukemia, lymphoma, multiple myeloma and other blood disorders.

Novartis data at ASCO and EHA showcase latest oncology research and innovation, including in breast and prostate cancer

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The U.S.-listed shares of Novartis AG NVS, -2.53% NOVN, -0.09% fell 2.6% in afternoon trading Thursday, after the Switzerland-based drug maker said it was "temporarily" suspending delivery of its cancer treatments Lutathera and Pluvicto in the U.S., as part of a quality review of its production sites in Millburn, New Jersey and Ivrea, Italy. The delivery suspension follows the company's "temporary, voluntary suspension" of production of its radioligand therapy production sites in New Jersey and Italy, which is due to "an abundance of caution" while it addresses potential quality issues identified in its manufacturing process.

Novartis suspends delivery of cancer treatment as it address potential production issues

Basel, May 4, 2022 — Novartis today announced updated median overall survival (OS) results for Kisqali® (ribociclib) in combination with fulvestrant in the first-line subgroup of postmenopausal women with hormone receptor-positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) advanced or metastatic breast cancer. The analysis of patients treated in first-line with Kisqali plus fulvestrant demonstrated a significant OS benefit of nearly 16 months compared to those treated with fulvestrant alone. This updated exploratory OS analysis from the Phase III MONALEESA-3 study will be presented as a late-breaker mini-oral presentation at the 2022 European Society of Medical Oncology (ESMO) Breast Cancer Congress (Abstract #LBA4).

New Novartis data demonstrate only Kisqali® offers more life in the first-line setting for postmenopausal HR+/HER2- advanced breast cancer patients

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Novartis AG (NYSE: NVS) has announced topline results from an interim analysis of the Phase 3 RATIONALE 306 study of tislelizumab plus chemotherapy in esophageal squamous cell carcinoma (ESCC). Data showed that tislelizumab plus chemotherapy significantly improved overall survival (.

Novartis - BeiGene's Tislelizumab Aces Late-Stage Esophageal Cancer Trial

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Molecular Partners, Novartis Note EUA For COVID-19 Therapy May Need Additional Data

Basel, April 27, 2022 — Novartis today announced positive topline results from an interim analysis of the Phase III RATIONALE 306 study, which showed anti-PD-1 immune checkpoint inhibitor tislelizumab plus chemotherapy significantly improved overall survival (OS) compared to chemotherapy in patients with previously untreated unresectable, locally advanced, recurrent or metastatic esophageal squamous cell carcinoma (ESCC), regardless of PD-L1 expression. Novartis intends to submit these data to regulatory authorities, and will collaborate with BeiGene to present them at an upcoming medical meeting.

Novartis tislelizumab plus chemotherapy significantly improved overall survival as first-line treatment for advanced esophageal cancer in Phase III study

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Novartis: Comment On Q1 Results

Novartis (NVS) beats on earnings in the first quarter but sales lag expectations. Generic Sandoz business returns to growth.

Novartis (NVS) Beats on Q1 Earnings, Sandoz Posts Growth

Novartis AG (NYSE:NVS ) Q1 2022 Earnings Conference Call April 26, 2022 8:00 AM ET Company Participants Samir Shah - Global Head, Investor Relations Vasant Narasimhan - Chief Executive Officer Harry Kirsch - Chief Financial Officer Conference Call Participants Graham Parry - Bank of America Simon Baker - Redburn Matthew Weston - Credit Suisse Wimal Kapadia - Bernstein Andrew Baum - Citi Richard Vosser - JPMorgan Emmanuel Papadakis - Deutsche Bank Emily Field - Barclays Tim Anderson - Wolfe Research Peter Welford - Jefferies Keyur Parekh - Goldman Sachs Florent Cespedes - Societe Generale Sarita Kapila - Morgan Stanley Steve Scala - Cowen Laura Sutcliffe - UBS Seamus Fernandez - Guggenheim Securities Kerry Holford - Berenberg Naresh Chouhan - Intron Health Richard Parkes - BNP Paribas Graham Parry - Bank of America Matthew Weston - Credit Suisse Andrew Baum - Citi Steve Scala - Cowen Operator Good morning and good afternoon. And welcome to the Novartis Q1 2022 Results Release Conference Call and Live Webcast.

Novartis AG (NVS) CEO Vasant Narasimhan on Q1 2022 Results - Earnings Call Transcript

Sales of the company's heart failure treatment Entresto rise 39% in the first quarter.

Novartis Earnings Get a Boost From Sales of Its Key Drugs

Sales of heart failure treatment Entresto rise 39% in the first quarter.

Novartis Earnings Get Boost From Sales of Key Drugs

Novartis on Tuesday posted rising earnings and sales for the first quarter of the year as its key drugs drove the business and generics division Sandoz continued to normalize after Covid-19 headwinds.

Novartis posts higher net profit of $2.22 billion on sales of $12.53 billion

Core operating income at Novartis edged 3% higher in the first quarter as sales growth from new drugs was partly offset by unfavourable currency effects.

Novartis earnings edge higher on Cosentyx, Entresto

Ad hoc announcement pursuant to Art. 53 LR

Novartis delivers solid sales and profit growth. Strong performance of in-market brands supports confidence in mid-term growth outlook

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Novartis recently joined Snowflake's newly-launched Healthcare Data Cloud, which aims to create an integrated and cross-cloud data platform.

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